Pragmatic Phase III Randomized Trial of Proton versus Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial
Study Title
Pragmatic Phase III Randomized Trial of Proton versus Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial
Purpose
To compare 2 types of standard care radiation treatment: photon and proton, to find out which type is best for treating non-metastatic breast cancer.
Eligibility
Females or males diagnosed with invasive mammary carcinoma (ductal, lobular, or other) of the breast who have undergone either mastectomy or lumpectomy with any type of axillary surgery or axillary sampling
Patients who have undergone any type of reconstruction are allowed
Bilateral breast cancer is permitted
Patients proceeding with breast/chest wall & nodal radiation therapy including internal mammary node treatment
Age ≥ 21 years
You Cannot:
Have cancer anywhere else
Have any prior radiation treatment for current breast cancer
Study Process
The total duration of this study is up to 10 years. The study consists of 3 periods:
Pre-Radiation Treatment Period- within 30 days prior to radiation treatment starting
Radiation Treatment Period- Daily (Monday-Friday) for approximately 5 to 7 weeks
Follow Up Period- At 1 month, 6 months, & yearly from end of radiation treatment.
Interested in more information on this clinical research study?
Contact WK Cancer Center Clinical Research Department at 318-212-8671
Trial Details
Investigator:
Lane Rosen, M.D.
IRB:
University of Pennsylvania IRB
IRB Number:
UPCC 19115
Trial Type:
NA
Sponsor:
University of Pennsylvania
Contact Information:
http://cancer.wkhs.com