Study Title
A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer (COMPPARE)
Purpose
To determine if prostate cancer patients treated with proton therapy, as compared to IMRT, experience:
Improved quality of life
Reduced toxicity
Non-inferior or even superior cancer control
To determine if Hypofractionated proton therapy is non-inferior to standard fractionated proton therapy in patient-reported outcomes & physician-reported toxicity.
Eligibility
Males 30-80 years old
With localized, non-metastatic adenocarcinoma of the prostate
Low-risk, intermediate-risk, or high-risk disease
With a life expectancy estimation of at least 10 years
No previous prostate cancer treatment except for ADT
Performance Status 0-2
You Cannot:
Have cancer anywhere else
Have very low-risk or very high-risk prostate cancer
Have any prior prostate surgery, other than biopsy
Have had any prior pelvic radiation treatment
Study Process
The total duration of this study is up to 10 years. The study consists of 3 periods:
Pre-Radiation Treatment Period
Radiation Treatment Period- Daily Radiation treatments (Monday-Friday) & Weekly visits with the physician
Follow Up Period- At 3 month, 6 months, & yearly from end of radiation treatment
Interested in more information on this clinical research study?
Contact WK Cancer Center Clinical Research Department at 318-212-8671
Trial Details
Investigator:
IRB:
University of Florida
IRB Number:
Trial Type:
NA
Sponsor:
Patient Centered Outcomes University of Florida
Contact Information:
Radiation Oncology Services